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Table 1 Demographic characteristics and baseline values for sleep variables

From: Effects of eszopiclone on safety, subjective measures of efficacy, and quality of life in elderly and nonelderly Japanese patients with chronic insomnia, both with and without comorbid psychiatric disorders: a 24-week, randomized, double-blind study

Characteristic

Elderly

Elderly

Nonelderly

Nonelderly

1 mg

2 mg

2 mg

3 mg

Witha

Withoutb

Witha

Withoutb

Witha

Withoutb

Witha

Withoutb

(n = 38)

(n = 42)

(n = 42)

(n = 41)

(n = 43)

(n = 41)

(n = 37)

(n = 40)

Age, y, mean (SD)

71.5 (5.0)

69.5 (3.9)

70.3 (5.1)

71.0 (4.4)

37.3 (10.7)

43.0 (10.1)

37.6 (9.1)

45.9 (12.2)

Sex, n (%)

Male

20 (52.6)

15 (35.7)

20 (47.6)

14 (34.1)

11 (25.6)*

18 (43.9)

22 (59.5)

19 (47.5)

Female

18 (47.4)

27 (64.3)

22 (52.4)

27 (65.9)

32 (74.4)*

23 (56.1)

15 (40.5)

21 (52.5)

Body mass index, kg/m2, mean (SD)

22.8 (3.4)

23.1 (3.1)

23.1 (3.3)

23.5 (3.3)

22.6 (4.2)

24.0 (4.2)

23.3 (4.0)

22.5 (3.2)

Sleep latency, min

Mean (SD)

63.3 (44.0)

67.4 (37.4)

71.8 (49.6)

69.7 (45.1)

78.5 (62.8)

64.8 (41.3)

65.7 (46.0)

62.4 (38.9)

Median

60.0

60.0

60.0

60.0

60.0

60.0

60.0

55.0

Total sleep time, min

Mean (SD)

317.6 (77.1)

311.1 (70.4)

310.2 (67.2)

305.6 (52.4)

296.5 (46.8)

284.7 (40.6)

315.3 (60.5)

301.6 (54.9)

Median

330.0

310.0

330.0

300.0

300.0

290.0

330.0

300.0

Wake time after sleep onset, min

Mean (SD)

66.7 (56.9)

57.1 (48.1)

65.6 (63.0)

72.1 (63.6)

51.7 (41.5)

54.9 (42.6)

40.8 (40.5)

43.8 (41.6)

Median

60.0

40.0

35.0

50.0

40.0

60.0

30.0

33.8

  1. a Insomnia with comorbid psychiatric disorders.
  2. b Insomnia without comorbid psychiatric disorders.
  3. *P < 0.01 vs nonelderly patients with psychiatric disorders receiving 3 mg eszopiclone.
  4. P < 0.05 vs nonelderly patients without psychiatric disorders receiving 3 mg eszopiclone.
  5. P < 0.05 vs nonelderly patients with psychiatric disorders receiving 3 mg eszopiclone.
  6. SD = standard deviation.