Table 6 Sleep variables at baseline and Week 25 (after discontinuation of eszopiclone)
Measure | Elderly | Elderly | Nonelderly | Nonelderly | ||||
|---|---|---|---|---|---|---|---|---|
1 mg | 2 mg | 2 mg | 3 mg | |||||
Baseline | Week 25 | Baseline | Week 25 | Baseline | Week 25 | Baseline | Week 25 | |
Sleep latency, min | n = 80 | n = 74 | n = 83 | n = 78 | n = 84 | n = 71 | n = 77 | n = 62 |
Mean (SD) | 67.8 (42.3) | 50.8 (47.8) | 76.2 (48.9) | 70.7 (81.2) | 75.5 (51.3) | 65.4 (67.3) | 70.8 (46.4) | 61.5 (66.3) |
Median | 60.0 | 30.0 | 60.0 | 40.0 | 60.0 | 40.0 | 60.0 | 30.0 |
Total sleep time, min | n = 80 | n = 74 | n = 83 | n = 78 | n = 84 | n = 71 | n = 77 | n = 62 |
Mean (SD) | 311.0 (68.9) | 340.0 (96.3) | 299.3 (59.8) | 328.7 (102.3) | 282.0 (47.7) | 315.3 (61.1) | 312.4 (67.1) | 336.3 (80.6) |
Median | 330.0 | 360.0 | 300.0 | 360.0 | 290.0 | 300.0 | 300.0 | 337.5 |
Wake time after sleep onset, | ||||||||
min | n = 79 | n = 74 | n = 82 | n = 77 | n = 84 | n = 71 | n = 77 | n = 62 |
Mean (SD) | 70.8 (57.8) | 46.0 (49.1) | 77.2 (64.8) | 50.8 (53.3) | 70.3 (65.5) | 28.0 (32.6) | 50.2 (42.0) | 35.7 (54.0) |
Median | 60.0 | 30.0 | 60.0 | 30.0 | 60.0 | 15.0 | 45.0 | 15.0 |
Number of awakenings | n = 80 | n = 74 | n = 83 | n = 77 | n = 84 | n = 71 | n = 77 | n = 62 |
Mean (SD) | 2.1 (0.9) | 1.6 (1.0) | 2.2 (1.0) | 2.0 (1.1) | 1.9 (1.0) | 1.2 (1.0) | 1.9 (1.4) | 1.7 (1.7) |
Median | 2.0 | 2.0 | 2.0 | 2.0 | 2.0 | 1.0 | 2.0 | 1.0 |
Quality of sleep * | n = 80 | n = 74 | n = 83 | n = 78 | n = 84 | n = 71 | n = 77 | n = 62 |
Mean (SD) | 4.1 (1.8) | 5.4 (2.3) | 4.2 (1.8) | 5.3 (2.5) | 3.4 (1.2) | 4.5 (2.2) | 4.1 (1.7) | 4.8 (2.8) |
Median | 4.0 | 5.0 | 4.0 | 5.0 | 3.0 | 4.0 | 4.0 | 5.0 |
Depth of sleep * | n = 80 | n = 74 | n = 83 | n = 78 | n = 84 | n = 71 | n = 77 | n = 62 |
Mean (SD) | 4.2 (1.9) | 5.4 (2.3) | 4.3 (2.1) | 5.1 (2.6) | 3.3 (1.2) | 4.7 (2.1) | 4.1 (1.8) | 4.8 (2.7) |
Median | 4.0 | 5.0 | 4.0 | 5.0 | 3.0 | 4.0 | 4.0 | 5.0 |
Daytime sleepiness * | n = 80 | n = 74 | n = 83 | n = 78 | n = 84 | n = 71 | n = 77 | n = 62 |
Mean (SD) | 5.1 (2.2) | 6.2 (2.3) | 5.0 (1.9) | 6.0 (2.4) | 4.1 (1.7) | 4.9 (2.3) | 4.7 (2.1) | 5.5 (2.6) |
Median | 5.0 | 6.0 | 5.0 | 6.0 | 4.0 | 5.0 | 5.0 | 6.0 |
Daytime ability to function * | n = 80 | n = 74 | n = 83 | n = 78 | n = 84 | n = 71 | n = 77 | n = 62 |
Mean (SD) | 5.6 (2.1) | 6.7 (2.1) | 5.6 (2.0) | 6.4 (2.2) | 4.5 (1.7) | 5.6 (2.1) | 4.9 (1.9) | 5.9 (2.5) |
Median | 5.5 | 7.0 | 5.0 | 7.0 | 4.5 | 5.0 | 5.0 | 6.0 |