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Table 1 Base case input parameters

From: Estimated economic benefits from low-frequency administration of atypical antipsychotics in treatment of schizophrenia: a decision model

Base Case Modifiable Inputs

 

LFA

RIS-LAI

RIS-SOT

Source

Adherence

1.0*

0.85*

0.65**

** [21]

Annual Discontinuation (Persistence)

0.30

0.50

0.64

[20, 23]

Annual Relapse Rates

When Adherent

10.10%

  

[15]

When Non-adherent

78.70%

  

Proportion of Relapses Inpatient

0.53

  

Utilities

 

While Stable

In Inpatient Relapse

In Outpatient Relapse

 

Adherent

0.88

0.53

0.74

[24]

Non-adherent

0.75

0.42

0.63

 

Execution

Model Timeframe

5 years

N/A

Cycle Length

1.0 months

Discount rate (costs)

3%