Table 3 Changes for study participants during the study

Systolic blood pressure, mmHg:

Baseline

116.4

107.5

At end of study (LOCF)

120.6

102.8

0.007

Diastolic blood pressure, mmHg:

Baseline

72.8

68.1

At end of study (LOCF)

76.7

68.9

0.009

Heart rate, beats/min:

Baseline

66.8

70.0

At end of study (LOCF)

69.6

72.1

Respiratory rate, breaths/min:

Baseline

14.7

14.8

At end of study (LOCF)

16.2

15.3

Body temperature smoking, °C:

Baseline

36.4

36.1

At end of study (LOCF)

36.5

36.3

Mean weight, kg:

Baseline

80.9

67.9

At end of study (LOCF)

81.4

68.5