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Table 3 Changes for study participants during the study

From: Atomoxetine treatment for nicotine withdrawal: a pilot double-blind, placebo-controlled, fixed-dose study in adult smokers

Characteristics Atomoxetine arm (N = 9) Placebo arm (N = 8) P value (if significant)
Systolic blood pressure, mmHg:    
Baseline 116.4 107.5  
At end of study (LOCF) 120.6 102.8 0.007
Diastolic blood pressure, mmHg:    
Baseline 72.8 68.1  
At end of study (LOCF) 76.7 68.9 0.009
Heart rate, beats/min:    
Baseline 66.8 70.0  
At end of study (LOCF) 69.6 72.1  
Respiratory rate, breaths/min:    
Baseline 14.7 14.8  
At end of study (LOCF) 16.2 15.3  
Body temperature smoking, °C:    
Baseline 36.4 36.1  
At end of study (LOCF) 36.5 36.3  
Mean weight, kg:    
Baseline 80.9 67.9  
At end of study (LOCF) 81.4 68.5  
  1. LOCF = last observation carried forward.