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Table 4 Serum cytokine concentrations in 41 women with perimenopausal depression, subdivided into those receiving (n = 19) or not (n = 22) selective serotonin reuptake inhibitors (SSRIs) compared to those women without perimenopausal depression (n = 24)

From: The role of cytokines and hot flashes in perimenopausal depression

Cytokine Perimenopausal women with depression Perimenopausal women without depression, N = 24 P value, Kruskal-Wallis
  Not treated with SSRIs, N = 22 Treated with SSRIs, N = 19   
TNFα 9.84 (2.3 to 21.90) 6.31 (4.08 to 9.23) 6.66 (3.01 to 16.50) 0.215, NS
IL-6 1.75 (1.13 to 2.95) 2.47 (1.59 to 4.67) 0.00 (0.00 to 5.63) 0.364, NS
IL-10 5.69 (3.39 to 12.00) 3.91 (1.08 to 10.20) 5.46 (1.31 to 12.90) 0.942, NS
  1. The results of cytokines are expressed as medians (10% to 90%). Unit of serum cytokine concentration is pg/ml.
  2. IL = interleukin; NS = not significant; TNF = tumor necrosis factor.