Skip to main content

Table 1 Adverse events in order of frequency

From: Review of the use of Topiramate for treatment of psychiatric disorders

Adverse events * Topiramate (N = 896) N (%)
Paresthesia/numbness 116 (12.9)
Nausea/vomiting 56 (6.2)
Cognitive impairment 48 (5.4)
Headache 46 (5.1)
Dizziness 45(5.0)
Sedation/drowsiness 44 (4.9)
Fatigue 38 (4.2)
Decreased appetite 24 (2.7)
Frequent peristalsis 20 (2.2)
Somnolence 19 (2.1)
Blurred vision 18 (2.0)
Slow memory 16 (1.8)
Lack of concentration 11 (1.2)
Influenza-like-symptoms 10 (1.1)
Panic/anxiety 9 (1.0)
Dysgeusia 8 (0.9)
Dry mouth 8
Nervousness 7 (0.8)
Rash 7
Ataxia 7
Insomnia 7
Constipation 7
Reduced libido 5 (0.6)
Memory concerns 5
Dyspepsia 5
Unwanted weight loss 4 (0.4)
Increased thirst 4
Word-finding difficulty 4
Impaired concentration 4
Tremor 4
Itching 4
Sweating 3 (0.3)
Confusion 3
Slowed thinking 3
Psychosis 3
Slurred speech 3
Increased salivation 3
Sleep disturbance 3
Backache 3
Increased appetite 2 (0.2)
Gastrointestinal disturbances 2
Agitation 2
Cold sensitivity 2
Worsening of symptoms 2
Increased libido 2
Amenorrhea 1 (0.1)
Hematuria 1
Dysuria 1
Urticaria 1
Increased suicidality 1
Glaucoma 1
Water retention 1
Delirium 1
Grand mal seizures 1
  1. (*) From the studies reviewed only