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International Society on Brain and Behaviour: 2nd International Congress on Brain and Behaviour
Annals of General Psychiatry volume 5, Article number: S92 (2006)
Background
Alzheimer's disease is the most common dementia (50–65%). It affects, mainly, people aged 65 and over. It attacks the brain resulting in a decline or loss of intellectual functions, such as remembering, thinking, speaking. Physical exercise improves physical, cognitive and functional abilities of the elderly, and contributes to better psychological function. Regular physical exercise appears to have a positive effect on Alzheimer's disease patients' cognitive abilities. The Aim of this project was the investigation of the hypothesis that a multifarious exercise programme may help Alzheimer's disease patients to maintain or enhance their cognitive abilities.
Materials and methods
Twenty four (24) patients with Alzheimer's disease (according to NICDS-ADRDA and DSM IV criteria for Alzheimer's disese) consisted the experimental (12 patients, 8 men and 4 women, mean age 65.70 years, and 9.33 years of education) and the control group (12 patients, 8 men and 4 women, mean age 68.50 years, and 8.92 years of education). The xperimental procedure lasted 36 weeks. The patients were all evaluated for their cognitive (MMSE) status, two weeks before and after the experimental manipulation.
Results
Paired Samples t-tests revealed that the patients of the experimental group managed to maintain their cognitive abilities (t(11) = 0.692, p = 0.504), while the patients of the control group deteriorated (t(11) = 3.570, p = 0.004).
Discussion
The implementation of a multifarious exercise programme designed to deal with the deficits and needs an Alzheimer's disease patient faces, may contribute in delaying the progress of the disease by preserving his/her cognitive abilities.
References
Lindenmuth G, Moose B: Improving cognitive abilities of elderly Alzheimer's patients with intense exercise therapy. The American Journal of Alzheimer's Care and Related Disorders and Research. 1990, 5: 31-33.
Mouzakidis C, Tsolaki M, Theodorakis Y, Efremidou E, Kambitsis C: Exercise program in patients with Alzheimer's disease. Alzheimer's disease and related disorders. 1999, 781-786.
Lytle ME, Vander Bilt J, Pandav RS, Dodge HH, Ganguli M: Exercise level and cognitive decline. The MoVIES project. Alzheimer Disease and Associated Disorders. 2005, 18: 57-64.
Voelkl JE, Galecki AT, Fries BE: Nursing home residents with severe cognitive impairements: Predictors of participation in activity groups. Therapeutic Recreation Journal. 1996, 27-40.
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Mouzakidis, C., Theodorakis, Y., Tsolaki, M. et al. International Society on Brain and Behaviour: 2nd International Congress on Brain and Behaviour. Ann Gen Psychiatry 5 (Suppl 1), S92 (2006). https://doi.org/10.1186/1744-859X-5-S1-S92
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DOI: https://doi.org/10.1186/1744-859X-5-S1-S92