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Table 4 Psychopharmacological treatment before admission to SPDC, during SPDC stay and at discharge. Percentages are calculated on patients under treatment at admission, during hospital stay and at discharge.

From: Clinical features and therapeutic management of patients admitted to Italian acute hospital psychiatric units: the PERSEO (psychiatric emergency study and epidemiology) survey

Type of drug At admission n (%) In SPDC n (%) At discharge n (%)
  Overall Females Males Overall Females Males Overall Females Males
Benzodiazepine 960 (58.6) 513 (42.3)* 447 (35.5)* 1927 (79.3) 964 (79.4) 963 (76.6) 1604 (68.0) 795 (65.5) 809 (64.3)
Atypical antipsychotic 700 (42.7) 321 (26.4)† 379 (30.1)† 1215 (50.0) 571 (47.0)† 644 (51.2)† 1222 (51.8) 577 (47.5) 645 (51.3)
Conventional antipsychotic 690 (42.1) 316 (26.6)† 374 (29.7)† 1268 (52.2) 575 (47.4)* 693 (55.1)* 1046 (44.4) 483 (39.8)† 563 (44.8)†
Antidepressant 591 (36.1) 361 (29.7)* 230 (18.3)* 808 (33.3) 476 (39.2)* 332 (26.4)* 795 (33.7) 464 (38.2)* 331 (26.3)*
Mood stabilizer 509 (31.1) 263 (21.7) 246 (19.6) 764 (31.5) 391 (32.2) 373 (29.7) 774 (32.8) 392 (32.3) 382 (30.4)
Anticholinergic 131 (8.0) 53 (4.4)† 78 (6.2)† 301 (12.4) 119 (9.8)* 182 (14.5)* 261 (11.1) 107 (8.8)§S 154 (12.2)§S
Other 67 (4.1) 28 (2.3)† 15 (1.2)† 215 (8.9) 92 (7.6)* 55 (4.4)* 101 (4.2) 43 (3.5)† 24 (1.9)†
Total no. of patients on treatment 1638 (66.3) 825 (68.0) 813 (64.6) 2429 (98.3) 1197 (98.6) 1232 (97.8) 2358 (95.4) 1161 (95.6) 1197 (95.2)
(% of total PERSEO population)          
  1. *Males versus females, p < 0.001; †males versus females, p < 0.05; §males versus females, p < 0.01
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