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Table 5 Effect of bupropion HCl 120 mg/kg intraperitoneal infusion times on the mean ± SD intensity of bupropion HCl-induced convulsions in mice

From: Effect of increasing intraperitoneal infusion rates on bupropion hydrochloride-induced seizures in mice

Group* Intraperitoneal (IP) infusion time (min) Mean ± SD intensity of convulsions
   Mild Moderate Severe
1 0 (bolus) 10.0 ± 12.9 5.5 ± 10.4 0
2 15 14.2 ± 17.4 7.1 ± 10.9 5.9 ± 13.1
3 30 9.2 ± 11.7 4.1 ± 6.4 2.8 ± 8.9
4 60 10.2 ± 16.4 4.6 ± 7.0 2.2 ± 4.8
5 90 0 0 0
6 120 2.8 ± 8.5 0.5 ± 1.6 0.1 ± 0.3
7 240 0 0 0
  1. *Number of mice was 10 for each group, except group 5 that had 9 mice.