Skip to content

Advertisement

  • Poster presentation
  • Open Access

Neurophysiological investigations in Trigeminal Neuralgia

  • 1,
  • 2,
  • 3 and
  • 4
Annals of General Psychiatry20087 (Suppl 1) :S238

https://doi.org/10.1186/1744-859X-7-S1-S238

  • Published:

Keywords

  • Trigeminal Neuralgia
  • Trigeminal Ganglion
  • Systematic Literature Review
  • Facial Pain
  • Entry Zone

Background

Trigeminal Neuralgia (TN) is a chronic neurological condition which is characterised by severe episodic facial pain. There are two main presentations of TN, the classical and the atypical. The classical TN is characterised by short periods of stabbing pain whish are associated with a small trigger zone and remits for varying periods. The atypical presentation has prolonged periods of burning pain, with a constant discomfort between attacks and a sensory impairment.

Materials and methods

The main aim was to show if there are quantifiable differences between classical and atypical TN. A systematic literature review was conducted, using relevant key words across major medical databases. All selected articles were scrutinized independently by the authors, in order to decide on each study's scientific merit, rigor of method and results.

Results

Twenty three 23 studies were identified, eighteen of which were included for analysis. These eighteen studies included clear observational and measurement descriptions of any activities recorded i.e. morphology, frequency, amplitude and peak latencies. Most studies used non-parametric tests like the Mann-Whitney test to determine whether there is any significant difference between symptomatic and quiescent states in each presentation group, and ANOVA to investigate whether there was any significance differences between each presentation in each state.

Conclusions

With regards to patients with the classical TN, spontaneous action potentials are seen from recordings in the trigeminal ganglion and “irritable” activity from the direct nerve recordings from the root entry zone. In patients with atypical TN, there does not exist a typical finding from each recording performed, while spontaneous activity is seen from the ganglion in both symptomatic and quiescent.

Authors’ Affiliations

(1)
MD, Neurophysiologist, Substitute Consultant, Papageorgiou Hosp, Thessaloniki, Greece
(2)
MSc, Clinical Collaborator, Nursing Dep., TEI, Thessaloniki, Greece
(3)
Neurologist, Papageorgiou Hosp, Thessaloniki, Greece
(4)
MD, Neurophysiologist, Consultant Neurologist, Papageorgiou Hosp, Thessaloniki, Greece

References

  1. Baumann TK, Burchiel KJ: A method for intraoperative microneurographic recording of unitary activity in the trigeminal ganglion of patients with Trigeminal neuralgia. Journal of Neuroscience Methods. 2004, 132: 19-24. 10.1016/j.jneumeth.2003.08.016.View ArticlePubMedGoogle Scholar
  2. Leandri M, Eldridge P, Miles J: Recovery of nerve conduction following Microvascular decompression for Trigeminal neuralgia. Neurology. 1998, 51 (6): 1641-6.View ArticlePubMedGoogle Scholar
  3. Burchiel KJ, Baumann TK: Pathophysiology of Trigeminal neuralgia: new evidence from a Trigeminal ganglion intraoperative microneurographic recording. Journal of Neurosurgery. 2004, 101: 872-873.View ArticlePubMedGoogle Scholar

Copyright

Advertisement