Volume 7 Supplement 1

International Society on Brain and Behaviour: 3rd International Congress on Brain and Behaviour

Open Access

Mild cognitive impairment: why bother?

  • Gabriel Gold1
Annals of General Psychiatry20087(Suppl 1):S49


Published: 17 April 2008

The existence of an intermediate zone between dementia and normal cognitive function has long been recognized. This terminology has evolved from that of “benign senescent forgetfulness” proposed by Kral in 1962 to the more modern concept of mild cognitive impairment (MCI) defined by Petersen in 1999. In many cases, MCI will eventually lead to a more severe condition consistent with a diagnosis of dementia. However, some cases may remain stable or even improve. Efforts towards a better prediction of conversion to dementia have led to modified criteria for MCI and the creation of clinical sub-groups within this entity. Although pharmacological trials in MCI have generally been disappointing, recognition of this condition may be crucial for the early detection of dementing processes and rapid initiation of therapeutic interventions to slow down or arrest the progression of dementia.

Authors’ Affiliations

Division of Internal Medicine and Rehabilitation, HUG


© Gold; licensee BioMed Central Ltd. 2008

This article is published under license to BioMed Central Ltd.