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Table 2 Case series linking isotretinoin and psychiatric side effects

From: Isotretinoin and psychopathology: a review

Reference Year No. of patients Psychiatric adverse effect
Meyskens [4] 1982 2 Psychological changes
Hazen et al. [5] 1983 6 Depression
Bruno et al. [18] 1984 22 Depressive symptoms
Bigby and Stern [19] 1983 3 Depression/violent behaviour
Scheinman et al. [20] 1990 7 Depression: suicide attempt (1)
Duke and Guenther [21] 1993 2 Depression
Bravard et al. [22] 1993 3 Depression: suicide attempts (2)
Byrne et al. [23] 1998 3 Depression: suicide attempt (1)
Barak et al. [24] 2005 5 Affective psychosis/suicide attempts (3)