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Table 8 Factors significantly associated with EQ-5D VAS over 6 months of AD treatment

From: The Factors Influencing Depression Endpoints Research (FINDER) study: final results of Italian patients with depression

Independent variables F, P value Estimate 95% CI
EQ-5D VAS at baseline 85, < 0.0001 0.33 0.26 to 0.40
Any psychiatric illnesses in the 24 months before baseline 18, < 0.0001 -7.18 -10.53 to -3.84
Switch within or between AD class (2 df) (reference no switch)   9, < 0.001 Between (NS)
   Within -15.51 -22.66 to -8.36
Occupational status (2 df, reference working for pay) 8, < 0.001 Other -4.16 -7.43- to -0.89
   Unemployed -8.46 12.77 to -4.14
Age 13, < 0.001 -0.18 -0.29 to -0.08
Overall pain VAS at baseline 8, 0.004 -0.08 -0.13 to -0.02
  1. No. of patients = 400, no. of observations = 795. Switch = change between what was taken between baseline and 3-month observation and what was taken between the 3-month and 6-month observations.
  2. AD = antidepressant; df = degrees of freedom; EQ-5D = European Quality of Life-5 Dimensions; VAS = visual analogue scale.