From: Lower paraoxonase 1 activity in Tunisian bipolar I patients
Variables | Bipolar I patients (n = 66) | Control subjects (n = 64) | P value | ||
---|---|---|---|---|---|
N | Mean ± SD | N | Mean ± SD | ||
Gender | |||||
Male | 46 | 170 ± 125 | 34 | 232 ± 95 | 0.01 |
Female | 20 | 180 ± 121 | 30 | 298 ± 75* | < 0.001 |
Age, years | |||||
< 25 | 11 | 124 ± 82 | 24 | 254 ± 87 | < 0.001 |
25-60 | 51 | 189 ± 131 | 32 | 266 ± 96 | 0.003 |
≥60 | 4 | 107 ± 51 | 8 | 274 ± 97 | 0.003 |
BMI, kg/m2 | |||||
< 25 | 28 | 162 ± 119 | 39 | 257 ± 101 | 0.001 |
25-30 | 22 | 186 ± 135 | 16 | 284 ± 86 | 0.008 |
≥30 | 16 | 175 ± 117 | 9 | 251 ± 52 | 0.04 |
Cigarette smoking | |||||
Yes | 34 | 180 ± 122 | 28 | 235 ± 92 | 0.04 |
No | 32 | 167 ± 125 | 36 | 284 ± 87* | < 0.001 |
Alcoholic beverages | |||||
Yes | 7 | 236 ± 121 | 14 | 243 ± 102 | 0.89 |
No | 59 | 166 ± 122 | 50 | 268 ± 89 | 2.10 × 106 |
Episode of illness | |||||
Depressive | 6 | 254 ± 174 | |||
Euthymic | 42 | 177 ± 123 | |||
Manic | 18 | 137 ± 94 | |||
Treatment | |||||
Lithium (A) | 5 | 73 ± 45 | |||
Carbamazepine (B) | 8 | 175 ± 114 | |||
Valproic acid | 31 | 180 ± 121 | |||
All mood stabilisers | 44 | 167 ± 117 | |||
Antipsychotics | 22 | 187 ± 137 |