Annals of General Psychiatry

Table 2 Clean urinalyses percentage of harm reduction and agonist opioid treatment patients according to substitution medication used

From: The newer Opioid Agonist Treatment with lower substitutive opiate doses is associated with better toxicology outcome than the older Harm Reduction Treatment

Modality	Medication	Clean urinalyses
Modality	Medication	Heroin	Cocaine	Cannabinoid
HRT	Buprenorphine (N = 87)	0.88 ± 0.2	0.91 ± 0.2	0.75 ± 0.3
	Methadone (N = 102)	0.79 ± 0.3	0.86 ± 0.2	0.68 ± 0.3
	Total (N = 189)	0.83 ± 0.2	0.88 ± 0.2	0.71 ± 0.3
OAT	Buprenorphine (N = 15)	0.97 ± 0.1	0.97 ± 0.1	0.83 ± 0.3
	Methadone (N = 43)	0.93 ± 0.1	0.97 ± 0.1	0.70 ± 0.4
	Total (N = 58)	0.94 ± 0.1	0.97 ± 0.1	0.73 ± 0.4
Total	Buprenorphine (N = 102)	0.89 ± 0.2	0.92 ± 0.2	0.76 ± 0.3
	Methadone (N = 145)	0.83 ± 0.2	0.89 ± 0.2	0.68 ± 0.3
	Total (N = 247)	0.86 ± 0.2	0.90 ± 0.2	0.72 ± 0.3

Between-subjects effects
Modality	Heroin urinalyses	F = 11.05; df = 1; p = 0.001
	Cocaine urinalyses	F = 11.09; df = 1; p = 0.001
	Cannabinoid urinalyses	F = 0.86; df = 1; p = 0.353
Medication	Heroin urinalyses	F = 3.98; df = 1; p = 0.047
	Cocaine urinalyses	F = 1.19; df = 1; p = 0.275
	Cannabinoid urinalyses	F = 3.73; df = 1; p = 0.055
Modality*medication	Heroin urinalyses	F = 0.68; df = 1; p = 0.409
	Cocaine urinalyses	F = 1.13; df = 1; p = 0.289
	Cannabinoid urinalyses	F = 0.37; df = 1; p = 0.542

Multivariate test: modality effect: F = 5.24; df = 3; p = 0.002. Medication effect: F = 1.97; df = 3; p = 0.118. Modality*medication effect: F = 0.77; df = 3; p = 0.512

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ISSN: 1744-859X

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