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Table 1 Demographics of participants

From: Multi-regression analysis revealed a relationship between l-serine and methionine, a component of one-carbon metabolism, in the normal control but not in the schizophrenia

  Schizophrenia Healthy control
Number of participant 45 30
Sex Male: 27 Male: 18
Age 50.6 ± 12.6 45.5 ± 13.0
Number of smoker 15 8
Duration of illness (years), mean ± SD 27.3 ± 12.8  
CP equivalent dose (mg/day), mean ± SD 667.58 ± 635.28  
l-serine (μM), mean ± SD 91.2 ± 21.1 85.6 ± 22.4
d-serine (μM), mean ± SD 1.50 ± 0.42 1.37 ± 0.45
Glycine (μM), mean ± SD 194.9 ± 64.0 176.5 ± 49.6
Vitamin B12 (pg/mL), mean ± SD 348.7 ± 132.6 309.5 ± 154.0
Folate (ng/mL), mean ± SD* 4.4 ± 1.7 5.7 ± 2.7
Homocysteine (μM), mean ± SD** 13.4 ± 8.3 9.1 ± 2.6
Methionine (μM), mean ± SD 13.1 ± 5.3 11.2 ± 7.1
PANSS score, mean ± SD 72.7 ± 17.9  
Positive, mean ± SD 14.4 ± 5.4  
Negative, mean ± SD 23.0 ± 6.0  
  1. Positive: subscale of positive syndrome scale in PANSS
  2. Negative: subscale of negative syndrome scale in PANSS
  3. CP chlorpromazine, SD standard deviation, PANSS positive and negative syndrome scale
  4. p < 0.05, ** p < 0.01