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Table 2 Changes of BPRS total scores of patients who fully or partly maintained the initial treatment from baseline to endpoint among the five kinds of antipsychotic drugs

From: The efficacy, acceptability, and safety of five atypical antipsychotics in patients with first-episode drug-naïve schizophrenia: a randomized comparative trial

Groups N BPRS total score at baseline BPRS total score at endpoint Deduction rate of BPRS total score
Aripiprazole 23 54.00 ± 10.39 29.96 ± 9.05 0.44 ± 0.13
Risperidone 23 56.04 ± 10.39 24.87 ± 7.05 0.55 ± 0.12ab
Quetiapine 27 58.48 ± 11.16 28.74 ± 6.21 0.50 ± 0.11
Olanzapine 21 53.10 ± 11.5 26.90 ± 4.75 0.47 ± 0.15
Ziprasidone 7 58.71 ± 14.59 25.86 ± 4.91 0.54 ± 0.13
F value   0.97 1.95 2.97
P value   > 0.05 > 0.05 0.023
  1. Deduction rate of BPRS score: (baseline BPRS total scores − post-treatment BPRS total scores)/baseline BPRS total scores. Values are represented as mean ± SD
  2. N: number of patients
  3. aComparison of risperidone with aripiprazole, P < 0.01
  4. bComparison of risperidone with olanzapine, P < 0.05