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Table 1 Demographic and clinical variables as predictors of non-adherence at bivariate level

From: Impact of adverse reactions to first-generation antipsychotics on treatment adherence in outpatients with schizophrenia: a cross-sectional study

Variables

Adherent

COR (95% CI)

p value

Yes

No

n (%)

n (%)

Gender

 Male

89 (57.1)

49 (57.0)

1.00 (0.59, 1.70)

0.991

 Female

67 (42.9)

37 (43.0)

Ref

 

Educational level

 Middle

30 (19.2)

24 (27.9)

3.00 (1.16, 7.73)

0.023a

 Secondary

68 (43.6)

45 (52.3)

2.48 (1.04, 5.90)

0.040a

 Higher

28 (17.9)

9 (10.5)

1.25 (0.41, 3.56)

0.735

 Primary/no formal education

30 (19.2)

8 (9.3)

Ref

 

Employment

 Unemployed

114 (73.1)

55 (64)

0.65 (0.37, 1.15)

0.140

 Employed

42 (26.9)

31 (36)

Ref

 

Marital status

 Single

67 (42.9)

43 (50)

2.09 (0.85, 5.03)

0.102

 Married

63 (404)

35 (40.7)

1.01 (0.74, 4.14)

0.195

 Divorced/widowed/separated

26 (16.7)

8 (9.3)

Ref

 

Residence

 Asmara

100 (64.1)

62 (72.1)

1.45 (0.81, 2.57)

0.207

 Out of Asmara

56 (35.9)

24 (27.9)

Ref

 

Smoking

 Yes

24 (15.4)

24 (27.9)

2.13 (1.12, 4.04)

0.021a

 No

132 (84.6)

62 (72.1)

Ref

 

Alcohol

 Yes

12 (7.7)

13 (15.1)

2.14 (0.93, 4.92)

0.074

 No

144 (92.3)

73 (84.9)

Ref

 

Number of APs

 Single

84 (53.8)

39 (45.3)

0.71 (0.42, 1.21)

0.206

 Multiple

72 (46.2)

47 (54.7)

Ref

 

ADRs-Counseling

 Yes

81 (51.9)

41 (47.7)

0.84 (0.50, 1.43)

0.527

 No

75 (48.1)

45 (52.3)

Ref

 

Drug formulation

 Long acting injectable

38 (24.4)

13 (15.1)

0.93 (0.51, 1.68)

0.806

 Oral and long acting injectable

69 (44.2)

44 (51.2)

0.54 (0.26,1.12)

0.097

 Oral

49 (31.4)

29 (33.7)

Ref

 

Variables

Adherent

 

COR (95% CI)

p value

 

Yes

No

  
 

Md (IQR)

Md (IQR)

  

Age

39.0 (16.0)

19.0 (15.0)

0.990 (0.9668,1.0139)

0.412

Weight

60.0 (18.0)

60.0 (12.0)

0.004 (0.9809, 1.0267)

0.758

Duration of illness

135.5 (144.0)

159.0 (163.3)

1.000 (0.9981, 1.0027)

0.734

Mean antipsychotic dose

196.2 (196.2)

237.5 (226.4)

1.002 (1.0001, 1.0037)

0.034a

Red herrings score

0.0 (2.0)

0.0 (4.0)

1.098 (1.0073, 1.1975)

0.033a

  1. COR  Crude odds ratio, CI confidence interval, Md median, IQR inter quartile range, n number of participants
  2. aSignificant