Table 2 Demographic, pre-treatment and baseline predictors of suicidal behaviour
Variables of interest | Baseline suicidal behaviour | 12-month suicidal behaviour | ||||||
|---|---|---|---|---|---|---|---|---|
|  | Patients with suicidal behaviour (n = 30) | Patients without suicidal behaviour (n = 88) | OR (95% CI) | p value | Patients with suicidal behaviour (n = 8) | Patients without suicidal behaviour (n = 52) | OR (95% CI) | p value |
Socio-demographics | ||||||||
 Male/female sex, n (%) | 21(70.0)/9(30.0) | 69(78.4)/19(21.6) | 1.56 (0.61–3.95) | 0.352 | 4 (50.0)/4 (50.0) | 36/16 | 2.25 (0.50–10.14) | 0.291 |
 Age at entry, mean (SD) | 26.83 (7.49) | 25 (7.01) | 0.98 (0.93–1.04) | 0.504 | 30.13 (9.91) | 26.63 (7.60) | 0.95 (0.87–1.04) | 0.252 |
 Years of education, mean (SD) | 11.10 (3.60) | 11.28 (3.01) | 1.02 (0.89–1.16) | 0.786 | 11.88 (3.56) | 11.19 (3.33) | 0.94 (0.75–1.18) | 0.588 |
 Married/with partner, n (%) | 5 (16.7) | 9 (10.2) | 1.76 (0.54–5.73) | 0.351 | 1 (12.5) | 7 (13.46) | 1.34 (0.14–13.25) | 0.801 |
 Living alone, n (%) | 1 (3.3) | 11 (12.5) | 0.24 (0.03–1.95) | 0.183 | 0 (0) | 8 (15.38) | 0.000 | 0.999 |
 Employed/student, n (%) | 16 (53.3) | 51 (57.9) | 0.83 (0.36–1.91) | 0.659 | 6 (75.0) | 2 (3.85) | 2.20 (0.41–11.95) | 0.361 |
Pre-treatment illness characteristics | ||||||||
 Family history of mental disorder, n (%) | 20 (66.67) | 56 (63.6) | 1.14 (0.48–2.74) | 0.765 | 7 (87.5) | 1 (1.92) | 3.11 (0.35–27.43) | 0.307 |
 History of suicidal behaviour, n (%) | 18 (60.0) | 24 (27.3) | 4.00 (1.68–9.53) | 0.002 | 7 (87.5) | 1 (1.92) | 13.22 (1.51–116.01) | 0.020 |
 History of substance use, n (%) | 20 (66.67) | 55 (62.5) | 1.20 (0.50–2.87) | 0.682 | 6 (75.0) | 2 (3.85) | 2.03 (0.37–11.05) | 0.412 |
 History of alcohol abuse, n (%) | 15 (50.0) | 37 (42.0) | 1.38 (0.60–3.17) | 0.449 | 3 (37.5) | 5 (9.62) | 0.89 (0.19–4.11) | 0.877 |
Baseline clinical characteristics | ||||||||
 DUP, median (SD) days | 28.00 (984.61) | 92.00 (473.95) | 1.00 (0.99–1.00) | 0.204 | 19 (114.55) | 98 (770.42) | 1.00 (0.99–1.01) | 0.291 |
 Hospitalisation, n (%) | 27 (90.0) | 74 (55.7) | 1.70 (0.45–6.40) | 0.430 | 0 (0.0) | 8 (15.38) | 0.000 | 0.999 |
 Tobacco use, n (%) | 18 (60.0) | 49 (55.7) | 1.19 (0.51–2.77) | 0.680 | 6 (75.0) | 2 (3.85) | 2.57 (0.47–13.94) | 0.274 |
 Last-month baseline suicidal behaviour | – | – | – | – | 5 (62.5) | 3 (5.77) | 5.56 (1.16–26.70) | 0.032 |
Diagnostic categories | ||||||||
 Schizophrenia-spectrum disorder, n (%) | 11 (36.67) | 47 (53.4) | 0.51 (0.21–1.18) | 0.116 | 2 (25.0) | 6 (11.54) | 0.29 (0.05–1.55) | 0.146 |
 Affective psychosis, n (%) | 9 (30.0) | 12 (12.6) | 2.71 (1.01–7.31) | 0.048 | 4 (50.0) | 4 (7.69) | 3.33 (0.72–15.37) | 1.123 |
 Other psychosis, n (%) | 8 (26.7) | 29 (32.9) | 0.74 (0.29–1.86) | 0.522 | 2 (25.0) | 6 (11.54) | 1.11 (0.19–6.24) | 0.905 |
Symptom severity and functioning | ||||||||
 PANSS positive symptoms, mean (SD) | 20.67 (8.05) | 21.43 (8.14) | 1.01 (0.96–1.07) | 0.653 | 20.63 (7.84) | 18.85 (7.29) | 0.97 (0.88–1.07) | 0.521 |
 PANSS negative symptoms, mean (SD) | 17.53 (8.48) | 15.30 (6.98) | 0.96 (0.91–1.01) | 0.155 | 17.88 (6.643) | 17.31 (7.237) | 0.99 (0.89–1.09) | 0.832 |
 PANSS general symptoms, mean (SD) | 39.07 (9.81) | 34.91 (8.22) | 0.95 (0.90–0.99) | 0.031 | 39.63 (6.02) | 35.69 (9.34) | 0.96 (0.89–1.03) | 0.260 |
 BDI, mean (SD) | 18.47 (11.434) | 11.42 (8.93) | 0.93 (0.89–0.97) | 0.002 | 20.50 (12.11) | 12.48 (9.87) | 0.93 (0.87–1.00) | 0.054 |
 Depression, n (%) | 20 (66.7) | 32 (36.4) | 3.50 (1.46–8.39) | 0.005 | 6 (75.0) | 2 (3.85) | 4.80 (0.88–26.14) | 0.070 |
 GAF, mean (SD) | 44.17 (17.52) | 43.14 (18,62) | 0.99 (0.97–1.02) | 0.789 | 43.75 (15.53) | 48.00 (17.60) | 1.01 (0.97–1.06) | 0.516 |
 MARS, mean (SD) | 5.50 (1.78) | 6.23 (2.39) | 1.15 (0.96–1.39) | 0.130 | 5.75 (2.66) | 5.79 (2.30) | 0.97 (0.92–1.03) | 0.304 |
Laboratory | ||||||||
 Total cholesterol | 154.50 (32.56) | 153.07 (31.62) | 0.999 (0.986–1.012) | 0.830 | 170.88 (26.2) | 146.17 (30.518) | 0.97 (0.95–0.99) | 0.045 |