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Table 3 Demographic and clinical information according to ApoE rs429358 genotype of cases and controls in a Chinese sample

From: Association between clinical symptoms and apolipoprotein A1 or apolipoprotein B levels is regulated by apolipoprotein E variant rs429358 in patients with chronic schizophrenia

Variables

Cases (n = 506)

Health Controls (n = 421)

CT + CC

(n = 73)

TT

(n = 433)

t /X2

p value

p adjusted*

CT + CC

(n = 67)

TT

(n = 354)

t/X2

p

value

Age (years)

47.45 ± 10.04

47.36 ± 9.66

− 0.077

0.939

–

46.15 ± 13.14

46.16 ± 13.27

0.006

0.995

Sex

 Female (%)

19 (26.0)

91 (21.0)

0.922

0.337

–

38 (56.7)

210 (59.3)

0.158

0.691

 Male (%)

54(74.0)

342(79.0)

 

29 (43.3)

144 (40.7)

Years of eudcation

10.21 ± 10.91

8.72 ± 2.60

− 1.159

0.250

–

10.80 ± 11.52

9.14 ± 3.32

-1.164

0.248

Body mass index

23.55 ± 4.12

24.73 ± 3.85

2.131

0.034

–

25.00 ± 3.58

25.41 ± 4.20

0.734

0.464

Age of onset (years)

23.34 ± 5.58

22.98 ± 4.77

− 0.587

0.558

–

–

–

–

–

Duration of illness (years)

24.11 ± 9.56

24.53 ± 10.07

0.335

0.738

–

–

–

–

–

Mean daily dose (mg/day)

(chlorpromazine equivalents)

411.30 ± 180.56

386.20 ± 167.21

− 1.012

0.312

–

–

–

–

–

PANSS score

         

 Positive symptoms

12.34 ± 5.19

11.52 ± 4.71

− 1.357

0.175

0.073

–

–

–

–

 Negative symptoms

25.16 ± 8.63

23.45 ± 8.36

− 1.608

0.109

0.097

–

–

–

–

 General psychopathology

26.32 ± 6.09

25.47 ± 5.92

− 1.117

0.264

0.777

–

–

–

–

 Total score

63.82 ± 14.51

60.45 ± 14.39

− 1.849

0.065

0.087

–

–

–

–

 ApoA1 level ( g/L)

1.38 ± 0.40

1.52 ± 0.37

2.586

0.010

–

–

–

–

–

 ApoB level ( g/L)

0.86 ± 0.26

0.88 ± 0.26

0.606

0.545

–

–

–

–

–

 ApoA1/ApoB

1.71 ± 0.59

1.84 ± 0.64

1.448

0.148

–

–

–

–

–

  1. *Adjusted by BMI