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Table 1 Baseline characteristics of the study participants

From: Depression and anxiety in different hypertension phenotypes: a cross-sectional study

 

Cont

WhHT

non-ResHT

ResHT

N (male/female)

82 (31:51)

44 (22:22)

200 (91:109)

37 (14:23)

Age (years)

49.61 ± 18.28

44.12 ± 13.36

59.44 ± 13.24

65.55 ± 10.22

Duration of hypertension (years)

 − 

 − 

9.40 ± 9.11

17.44 ± 13.22

Diabetes [n (%)]

 − 

3 (3.7%)

32 (16%)

16 (43%)

CV disease [n (%)]

 − 

 − 

18 (9%)

12 (32%)

Current smoker [n (%)]

12 (15%)

8 (18%)

38 (19%)

7 (19%)

BMI (kg/m2)

24.35 ± 3.65

27.70 ± 5.62

28.80 ± 4.62

30.50 ± 3.45

Blood glucose (mmol/l)

4.90 (4.60–5.51)

5.15 (4.75–5.40)

5.49 (5.00–6.32)

6.28 (5.26–7.50)

GFR–EPI (ml/min/1.73m2)

79.31 ± 32.40

93.31 ± 30.09

81.69 ± 18.37

72.35 ± 24.24

Uric acid (µmol/l)

295.00 ± 72.97

307.61 ± 68.92

327.86 ± 81.82

351.59 ± 101.05

Total cholesterol (mmol/l)

5.41 ± 1.10

5.54 ± 1.38

5.41 ± 1.15

4.76 ± 1.33

LDL (mmol/l)

3.30 ± 0.97

3.56 ± 1.24

3.34 ± 1.03

2.73 ± 1.24

HDL (mmol/l)

1.64 ± 0.36

1.47 ± 0.37

1.38 ± 0.38

1.26 ± 0.32

Triglyceride (mmol/l)

0.96 (0.69–1.30)

1.17 (0.87–1.57)

1.48 (1.08–2.05)

1.53 (1.10–2.47)

Medication [n (%)]

 ACE-inhibitor

 − 

 − 

118 (59%)

24 (64.9%)

 ARB [n (%)]

 − 

 − 

29 (14.5%)

12 (32.4%)

 Calcium channel blocker

 − 

 − 

75 (37.5%)

28 (75.6%)

 Beta-blocker

 − 

 − 

89 (44.5%)

27 (72.9%)

 Diuretic

 − 

 − 

23 (11.5%)

33 (89.2%)

 Alfa-adrenergic receptor blocker

 − 

 − 

22 (11%)

19 (51.3%)

 Centrally acting agents

 − 

 − 

1 (0.5%)

 Direct acting vasodilators

 − 

 − 

1 (0.5%)

5 (13.5%)

 Antiplatelet drug

1 (1.2%)

 − 

42 (21%)

12 (32.4%)

 Statin

6 (7.3%)

1 (2.3%)

50 (25%)

12 (32.4%)

 Fibrate

 − 

7 (3.5%)

5 (13.5%)

 Alprazolam

1 (1.2%)

 − 

18 (9%)

2 (5.4%)

Number of antihypertensive medications

 0

82 (100%)

44 (100%)

 − 

 − 

 1

 − 

 − 

85 (42.5%)

 − 

 2

 − 

 − 

72 (36%)

 − 

 3

 − 

 − 

43 (21.5%)

16 (43.2%)

 4

 − 

 − 

 − 

9 (24.3%)

 5

 − 

 − 

 − 

9 (24.3%)

 6

 − 

 − 

 − 

2 (5.4%)

 7

 − 

 − 

 − 

1 (2.7%)

  1. Data are presented as mean ± standard deviation or median (interquartile ranges)
  2. Cont: healthy controls, WhHT: patients with white-coat hypertension, non-ResHT: chronic, non-resistant hypertensive patients, ResHT: chronic, resistant hypertensive patients, CV diseases: cardiovascular diseases, BMI: body mass index, GFREPI: glomerular filtration rate assessed by the chronic kidney disease epidemiology collaboration glomerular filtration rate equation, LDL: low-density lipoprotein, HDL: high-density lipoprotein, ACE: Aangiotensin converting enzyme, ARB: angiotensin II receptor blocker
  3. Categorical parameters are presented as n (%). Significant differences compared with Cont are signed as bold and italic characters