Table 2 Number and percentage of adults with intellectual disabilities prescribed anticholinergic medication by medication class (BNF chapter), in comparison with general population adults
BNF chapter | Adults prescribed anticholinergic medications (n = 4,701) | OR [95% CI], p value* | |
|---|---|---|---|
Intellectual disabilities (n = 1,654) | General population (n = 3,047) | ||
Gastro-intestinal system | 773 (46.7%) | 1,505 (49.4%) | 1.00 [0.88–1.13], p = 0.985 |
Cardiovascular system | 477 (28.4%) | 1,419 (46.6%) | 0.61 [0.53–0.71], p < 0.001 |
Respiratory system | 222 (13.4%) | 373 (12.3%) | 1.06 [0.88–1.27], p = 0.547 |
Central nervous system | 1,037 (62.6%) | 1,231(40.4%) | 2.23 [1.96–2.53], p < 0001 |
Infections | 9 (0.54%) | 53(1.7%) | 0.43 [0.21–0.86], p = 0.017 |
Endocrine system | 29 (1.8%) | 120 (3.9%) | 0.45 [0.29–0.68], p < 0.001 |
Obstetrics, gynaecology and urinary-tract disorders | 51 (3.1%) | 40 (1.3%) | 2.82 [1.83–4.34], p < 0.001 |
Musculoskeletal and joint diseases | 65 (3.9%) | 40 (1.3%) | 2.49 [1.69–3.67], p < 0.001 |