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Table 4 Respiratory dysfunction-related factors (dyspnea, anemia, greater number of lobes involved in chest CT and carbon dioxide retention (PaCO2 > 45 mmHg)) were associated with abnormal PSQI scores in the acute stage of COVID-19

From: Sleep disorders in the acute phase of coronavirus disease 2019: an overview and risk factor study

 

Total

Dyspnea (n, %)

p value

Anemia (n, %)

p value

The number of lobes involved in chest CT (mean ± SD)

p value

Total

Carbon dioxide retention (PaCO2 > 45 mmHg) (n, %)

p value

With

Without

With

Without

With

Without

Sleep quality

 Decreased

38

16 (42.11)

22 (57.89)

0.046*

8 (21.05)

30 (78.95)

0.797

3.92 ± 2.08

0.179

22

5 (22.73)

17 (77.27)

0.547

 Normal

15

2 (13.33)

13 (86.67)

2 (13.33)

13 (87.67)

3.00 ± 2.45

5

0 (0.00)

5 (100.00)

Sleep latency

 Prolonged

33

15 (45.45)

18 (54.55)

0.023*

9 (27.27)

24 (72.73)

0.139

4.19 ± 1.98

0.022*

15

5 (33.33)

10 (66.67)

0.047*

 Normal

20

3 (15.00)

17 (85.00)

1 (5.00)

19 (95.00)

2.74 ± 2.33

12

0 (0.00)

12 (100.00)

Sleep duration

 Decreased

35

14 (40.00)

21 (60.00)

0.196

8 (22.86)

27 (77.14)

0.506

3.94 ± 2.02

0.117

19

5 (26.32)

14 (73.68)

0.280

 Normal

18

4 (22.22)

14 (77.78)

2 (11.11)

16 (88.89)

2.88 ± 2.47

8

0 (0.00)

8 (100.00)

Sleep efficiency

 Decreased

24

11 (45.83)

13 (54.17)

0.097

8 (33.33)

16 (66.67)

0.036*

4.22 ± 1.98

0.095

13

4 (30.77)

9 (69.23)

0.165

 Normal

29

7 (24.14)

22 (75.86)

2 (6.90)

27 (93.10)

3.18 ± 2.31

14

1 (7.14)

13 (92.86)

Sleep disturbances

 With

47

17 (36.17)

30 (63.83)

0.623

8 (17.02)

39 (82.98)

0.684

3.80 ± 2.11

0.178

25

5 (20.00)

20 (80.00)

1.000

 Without

6

1 (16.67)

5 (83.33)

2 (33.33)

4 (66.67)

2.50 ± 2.81

2

0 (0.00)

2 (100.00)

Sleep medication usage

 With

10

3 (30.00)

7 (70.00)

1.000

3 (30.00)

7 (70.00)

0.582

3.80 ± 2.20

0.810

5

2 (40.00)

3 (60.00)

0.221

 Without

43

15 (34.88)

28 (65.12)

7 (16.28)

36 (83.72)

3.61 ± 2.24

22

3 (13.64)

19 (86.36)

Daytime dysfunction

 With

31

12 (38.71)

19 (61.29)

0.386

7 (22.58)

24 (77.42)

0.643

3.93 ± 2.02

0.296

19

5 (26.32)

14 (73.68)

0.280

 Without

22

6 (27.27)

16 (72.73)

3 (13.64)

19 (86.36)

3.27 ± 2.43

8

0 (0.00)

8 (100.00)

  1. The p values were obtained from independent-sample t tests for continuous data of the number of lung lobes involved in chest CT and chi-square tests and Fisher’s exact tests (total number < 40 or any expected number < 5) for categorical variables, including dyspnea, anemia and carbon dioxide retention
  2. *p < 0.05
  3. PSQI, Pittsburgh sleep quality index; CT, computerized tomography; PaCO2, partial pressure of arterial carbon dioxide