Gut microbiota and its relation to inflammation in patients with bipolar depression: a cross-sectional study

Table 2 Serum Inflammatory Factors in BD patients and HCs

Inflammatory factors	BD	HCs	P
Inflammatory factors	N = 72	N = 16	P
IL-2 (pg/ml, mean ± SD)	0.41 ± 0.25	0.74 ± 0.52	0.29
IL-4 (pg/ml, mean ± SD)	0.15 ± 0.17	0.18 ± 0.82	0.69
IL6 (pg/ml, mean ± SD)	17.72 ± 42.97	0.43 ± 0.38	0. 007
IL-10 pg/ml, (mean ± SD)	0.94 ± 1.47	0.95 ± 1.40	0.99
IL-17A (pg/ml, mean ± SD)	3.13 ± 9.39	0.99 ± 2.86	0.31
TNFα (pg/ml, mean ± SD)	1.89 ± 4.34	0.47 ± 0.44	0.045
CRP (mg/l, mean ± SD)	1.77 ± 2.87	0.32 ± 0.38	0.025
CD3 (%, mean ± SD)	65.86 ± 12.66	62.60 ± 12.73	0.34
CD4 (%, mean ± SD)	33.50 ± 9.33	33.05 ± 9.66	0.82
CD8 (%, mean ± SD)	27.82 ± 9.69	26.56 ± 9.17	0.62
NK (%, mean ± SD)	14.59 ± 6.82	17.91 ± 9.50	0.11

BD Bipolar disorder, HCs Healthy controls, CRP C-reactive protein, INF interferon, NK natural killer

ISSN: 1744-859X