Table 2 Demographic and clinical characteristics between enrolled patients with and without MetS, grouped by gender
Parameters | MetS (n = 73) | Non-MetS (n = 595) | Gender F (p -value) | Diagnosis F (p -value) | Gender × diagnosis F (p -value) | ||
|---|---|---|---|---|---|---|---|
Male (n = 16) | Female (n = 57) | Male (n = 228) | Female (n = 367) | ||||
Age—years | 31.08 ± 7.72 | 26.59 ± 5.55 | 29.10 ± 6.80 | 30.27 ± 7.47 | 2.50(0.114) | 0.66 (0.419) | 7.24 (< .001*) |
Course of disease—years | 6.70 ± 5.30 | 5.33 ± 3.88 | 5.15 ± 4.55 | 5.03 ± 4.91 | 1.16 (0.283) | 1.76 (0.185) | 0.80(0.371) |
Onset age—years | 24.37 ± 5.77 | 21.26 ± 4.69 | 23.95 ± 6.36 | 25.24 ± 6.51 | 0.96 (0.328) | 3.63 (0.057) | 5.59 (0.018*) |
MetS dimensions | |||||||
WC—cm | 86.53 ± 10.3 | 90.64 ± 6.52 | 76.74 ± 8.63 | 77.04 ± 7.89 | 3.39 (0.066) | 95.45 (< .001*) | 2.53 (0.112) |
FBG—mmol/L | 5.87 ± 0.50 | 5.65 ± 0.57 | 5.53 ± 0.49 | 5.58 ± 0.46 | 1.42 (0.234) | 8.24 (0.004*) | 3.70 (0.055) |
SBP—mmHg | 120.63 ± 14.82 | 127.46 ± 14.91 | 112.07 ± 11.09 | 111.15 ± 10.96 | 3.03 (0.082) | 53.71(< .001*) | 5.23 (0.023*) |
DBP—mmHg | 84.38 ± 10.94 | 84.95 ± 10.89 | 74.43 ± 7.29 | 73.69 ± 7.81 | 0.01 (0.944) | 80.06 (< .001*) | 0.31 (0.580) |
TG—mmol/L | 1.77 ± 0.55 | 1.73 ± 0.60 | 1.04 ± 0.51 | 1.00 ± 0.49 | 0.21 (0.646) | 94.79 (< .001*) | 0.00 (0.997) |
HDL-C—mmol/L | 1.22 ± 0.19 | 1.15 ± 0.14 | 1.17 ± 0.26 | 1.19 ± 0.23 | 0.53 (0.467) | 0.00 (0.950) | 1.41 (0.236) |
TC—mmol/L | 4.38 ± 0.70 | 4.39 ± 0.67 | 3.80 ± 0.69 | 3.77 ± 0.7 | 0.02 (0.8901) | 33.95 (< .001*) | 0.05 (0.828) |
LDL-C—mmol/L | 2.57 ± 0.81 | 2.53 ± 0.65 | 2.16 ± 0.55 | 2.12 ± 0.56 | 0.19 (0.661) | 23.22 (< .001*) | 0.00 (0.950) |
RBC—1012/L | 4.62 ± 0.30 | 4.78 ± 0.32 | 4.51 ± 0.52 | 4.53 ± 0.46 | 1.53 (0.216) | 6.89 (0.009*) | 1.05 (0.306) |
HGB—g/L | 139.62 ± 12.57 | 144.96 ± 12.08 | 135.14 ± 18.6 | 134.84 ± 16.98 | 0.99 (0.320) | 8.35 (0.004*) | 1.25 (0.264) |
WBC—109/L | 7.59 ± 2.28 | 7.86 ± 1.95 | 7.03 ± 2.14 | 6.66 ± 1.85 | 0.03 (0.866) | 9.02 (0.003*) | 1.19 (0.275) |
PLT—109/L | 263.81 ± 82.21 | 256.58 ± 52.17 | 243.25 ± 58.32 | 238.61 ± 56.1 | 0.49 (0.483) | 5.20 (0.023*) | 0.24 (0.878) |
BUN—mmol/L | 4.28 ± 1.22 | 4.08 ± 1.13 | 4.61 ± 1.79 | 4.48 ± 1.85 | 0.41 (0.524) | 2.02 (0.156) | 0.01 (0.908) |
CRE—mmol/L | 55.56 ± 17.42 | 61.78 ± 18.09 | 58.25 ± 12.01 | 57.22 ± 11.51 | 1.99 (0.160) | 0.26 (0.613) | 3.85 (0.050) |
UA—mmol/L | 425.4 ± 129.32 | 401.12 ± 83.15 | 417.84 ± 129.21 | 411.65 ± 125.79 | 0.64 (0.405) | 0.01 (0.936) | 0.25 (0.621) |
TSH—uIU/mL | 1.83 ± 0.73 | 1.74 ± 0.70 | 1.71 ± 0.71 | 1.67 ± 0.72 | 0.37 (0.543) | 0.75 (0.388) | 0.04 (0.835) |
FT3—pmol/L | 4.84 ± 0.75 | 4.68 ± 0.77 | 4.88 ± 0.67 | 4.86 ± 0.68 | 0.80 (0.372) | 1.21 (0.271) | 0.46 (0.498) |
FT4—pmol/L | 14.73 ± 2.32 | 15.53 ± 3.30 | 17.19 ± 3.20 | 17.11 ± 3.05 | 0.63 (0.429) | 19.35 (< .001*) | 0.93 (0.335) |
CGI-SI | 5.13 ± 0.72 | 5.09 ± 0.43 | 5.45 ± 0.61 | 5.36 ± 0.64 | 0.50 (0.482) | 10.63 (0.001*) | 0.09 (0.770) |
PANSS | 90.69 ± 14.54 | 84.74 ± 11.6 | 89.34 ± 11.32 | 89.2 ± 11.24 | 3.29 (0.070) | 0.86 (0.354) | 2.99 (0.084) |
Positive factor | 16.31 ± 3.24 | 15.18 ± 3.17 | 15.79 ± 3.60 | 16.06 ± 3.51 | 0.70 (0.403) | 0.12 (0.727) | 1.85 (0.174) |
Negative factor | 29.06 ± 7.19 | 27.09 ± 7.14 | 28.61 ± 6.34 | 28.13 ± 5.94 | 1.78 (0.183) | 0.10 (0.749) | 0.67 (0.413) |
Excitement factor | 12.44 ± 5.35 | 11.33 ± 4.64 | 12.88 ± 4.33 | 12.84 ± 4.41 | 0.77 (0.381) | 2.21 (0.138) | 0.66 (0.416) |
Anxiety/depression factor | 14.31 ± 4.29 | 14.30 ± 3.97 | 15.28 ± 4.74 | 15.74 ± 4.41 | 0.12 (0.734) | 3.30 (0.070) | 0.13 (0.718) |
Cognitive factor | 17.94 ± 5.78 | 16.53 ± 3.86 | 16.6 ± 4.58 | 16.34 ± 4.31 | 1.65 (0.199) | 1.39 (0.240) | 0.78 (0.377) |