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Table 3 Adverse Events Associated With Donepezil*

From: Current pharmacologic options for patients with Alzheimer's disease

Adverse Event†

Placebo (n = 355) (%)

Donepezil (n = 747) (%)

Nausea

6

11

Diarrhea

5

10

Insomnia

6

9

Vomiting

3

5

Muscle cramp

2

6

Fatigue

3

5

  1. * Eisai Inc.: Aricept® (donepezil hydrochloride tablets) [package insert]. Teaneck, NJ 1998 †Occurring in at least 5% of patients and more often than in patients receiving placebo.