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The Familial Mediterranean Fever from the modern postnonclassic scientific viewpoint


The Familial Mediterranean Fever (FMF) as a genetic disease with autosom-recessive transmitting mechasnism and a clinical unclear, enigmatic, aimlesely spread aseptic inflammation finds a new solution from the viewpoint of psychosomatic theory [1], where are covered integral (psychic, phisical), hierarchic, selfregulatory, selfdecveloping and selforganizing approaches. Somatoform disorders which exist among all the patients suffering from FMF [2] according to the modern FMF classification are not diagnosed and treated in time which is the reason for the progress of this disease as far as the internists diagnosed FMF only in case of availability of aseptic inflammation.

Materials and methods

Aseptic inflammmation [3] is connected with the consequence of the traumas borne in the past which are realized in the unfavourable conditions of the present life, when the disease is gradually deepening as mentioned above. The aseptic inflammation according tothe self regulating mechanism of the organism is the replying reaction to the trauma, which is becoming more and more frequent, as the aptients suffering from FMF and having bad psychological defensive mechanisms are adapted to the exteriorworld with difficulty. The frequently processing un-regulatory aseptic inflammations represent a great danger for the regulationof homeostasis, which according to the approach of self-regulatio the body responses with overspread ameloidosis.


The deepening of ameloidosis which leads to the death of the patients, strengthens the patient's hopelessness in the struggle for life, as they know that they are suffering from incurable disease and can see the how ends ameloidosis on their relatives. Thus the system leads him to death, disarrangement of the desorganism, development of enthropy.


The dynamic process – the system can be regulated with psychotherapy, bringing the system to regulation, the dicrese if enthropy, the disappearance of the attacks and the prevention and treatment of ameloidosis, which can be observed among our recovered patients.


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Open Access This article is published under license to BioMed Central Ltd. This is an Open Access article is distributed under the terms of the Creative Commons Attribution 2.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Nersisyan, A., Danielyan, K. & Nazaretyan, E. The Familial Mediterranean Fever from the modern postnonclassic scientific viewpoint. Ann Gen Psychiatry 5 (Suppl 1), S129 (2006).

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