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Temperament and character inventory (TCI) personality profile of alcohol misuse patients with and without a co-occurring mood or anxiety disorder

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Annals of General Psychiatry20087 (Suppl 1) :S110

  • Published:


  • Mental Disorder
  • Anxiety Disorder
  • Alcohol Abuse
  • Comorbid Disorder
  • Common Risk Factor


Alcohol use disorders (AUDs) are among the leading public health problems nowadays. Very often they co-occur with other psychiatric disorders, especially mood and anxiety disorders.

Quite a few studies exist that explore personality characteristics in individuals with alcohol misuse and a co-occuring mental disorder.

Such studies are of primary importance if we are to test the hypothesis that certain genetically inherited personality traits are a common risk factor for AUD and various externalizing and internalizing mental disorders.

Materials and methods

We examined two statistically matched groups (20 patients in each) of AUD patients (ICD-10 diagnosis of alcohol abuse or dependence). The first group consisted of patients with a lifetime diagnosis of mood/and or anxiety disorder and the second group included AUD patients without comorbid disorders. Lifetime psychiatric history was assessed “Composite International Diagnostic Interview” ver. 2.1 /lifetime/.

All the participants filled in the “Temperament and Character Inventory” self-evaluation questionnaire [1]. Data were processed with Statgraphics ver. 8.0.


Preliminary results (the study is still ongoing) show that patients with a co-occurring mood and/or anxiety disorder tend to score much higher on harm-avoidance and lower on self-directedness subscales.

Taken together, these results may be interpreted as a higher propensity to personality deviations in these patients, most likely from the so-called cluster “C” personality register [2].


Additional studies with larger sample sizes are needed to further investigate the complex interaction and causal relationships between mood and anxiety disorders and alcohol misuse.

Authors’ Affiliations

Department of Psychiatry, Pleven Medical University, Pleven, Bulgaria


  1. Cloninger C. R., Svrakic D. M., Przybeck T. R.: A psychobiological model of temperament and character. Archives of General Psychiatry. 1993, 50: 975-990.View ArticleGoogle Scholar
  2. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders. 1994, Washington, DC. American Psychiatric Association, 4-th EditionGoogle Scholar


© Stoichev et al.; licensee BioMed Central Ltd. 2008

This article is published under license to BioMed Central Ltd.