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Annals of General Psychiatry

Open Access

Pathopsychophysiological mechanism of low academic performance among drinkers

  • Menizibeya Welcome Osain1 and
  • Vladimir Pereverzev Alekseevic1
Annals of General Psychiatry20109(Suppl 1):S234

Published: 22 April 2010


AlcoholCognitive FunctionAcademic PerformanceGlucose ControlCentral Component


How alcohol use affect academic performance of students is not fully understood. It was recently shown that alcohol use reduces academic performance of university students by 6.6-12.1% [1]. But, in spite of the enormous epidemiological data regarding students' problem drinking, the fact that alcohol use leads to a decrease in academic performance remains disputable. This study considers several data that have helped us unravel this disbelief.

Materials and methods

Peer reviewed publications from Elsevier, Medline and African Index Medicus from 1930 to June 30th, 2009 on the effect of alcohol use on academic performance, cognitive functions and metabolism were critically analyzed. Our data (based on the psychophysiological functions of university students for a three years period of study and follow-up) were examined. We produced a system of academic performance: the psychophysiological concept of academic performance, where the major components - motivational and demotivational factors are located in a center of cognition and metabolic balance.


Distortment of the major elements of the system of academic performance like cognition and a negative shift in metabolic balance can result in low academic performance. A metabolic shift in important substrates (like glucose) for brain functions affects the equilibrium state of this system. This is because cognitive functions are dependent on the blood-brain glucose control systems [24]. Alcohol use can affect the metabolic equilibrium state of the system in a drinker, subsequently leading to a distortment of cognition (a central component of the system). This distortment however, can be modulated by motivational or demotivational factors. The strength of the modulating factors (genetic, metabolic counter-regulatory systems, environmental factors) determines the level of academic performance.


This study solves the question: If alcohol use leads to low academic performance; can't poor academic performance result in alcohol use? A full understanding of the effect of alcohol use on academic performance lies on the psycho-physiological system of academic performance.

Authors’ Affiliations

Department of Human Physiology, Belarusian State Medical University, Minsk, Belarus


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© Osain and Alekseevic; licensee BioMed Central Ltd. 2009

This article is published under license to BioMed Central Ltd.