Annual suicide rates of Hungary were unexpectedly high in the previous century. In our narrative review, we try to depict, with presentation of the raw data, the main descriptive epidemiological features of th...
Authors: Zoltan Rihmer, Xenia Gonda, Balazs Kapitany and Peter Dome
It has been reported that oral health is poor in elderly populations and is associated with poor cognition and dementia. The objective of this study was to examine the association between tooth loss and cognit...
This observational study documented heart rate over the entire course of electrically induced seizures and aimed to evaluate the effects of stimulus electrode placement, patients' age, stimulus dose, and addit...
Little focus has been paid to the role of poor mental health and childhood abuse among young people with regard to human immunodeficiency virus (HIV) risk behaviour and HIV prevention in Africa. The aim of thi...
Authors: Karl Peltzer, Supa Pengpid and Issaka Tiembre
Considered as a moment of psychological vulnerability, adolescence is remarkably a risky period for the development of psychopathologies, when the choice of the correct therapeutic approach is crucial for achi...
Authors: Nádia NR Lima, Vânia B Nascimento, Jorge AC Peixoto, Marcial M Moreira, Modesto LR Neto, José C Almeida, Carlos AC Vasconcelos, Saulo A Teixeira, Jucier G Júnior, Francisco TC Junior, Diego DM Guimarães, Aline Q Brasil, Jesus S Cartaxo, Marco Akerman and Alberto OA Reis
Khat is a well-known natural stimulant from the Catha edulis plant and is widely used in certain Red Sea countries, including Yemen and the province of Jazan in Saudi Arabia. Jazan is located in the southwestern ...
Authors: Mohamed Salih Mahfouz, Rashad Mohammed Alsanosy and Abdelrahim Mutwakel Gaffar
Studies on mental health problems during childhood and youth development phases have reported that families of children diagnosed with a depressive disorder tend to be dysfunctional. These dysfunctions have be...
Authors: Lincoln I Khasakhala, David Musyimi Ndetei, Muthoni Mathai and Valerie Harder
The therapeutic alliance is related to better course and outcome of treatment in schizophrenia. This study explores predictors and characteristics of the therapeutic alliance in recent-onset schizophrenia spec...
Authors: Ragnhild Johansen, Valentina C Iversen, Ingrid Melle and Knut A Hestad
Suicide is a major cause of death among youths particularly with psychiatric, alcohol abuse and substance abuse disorders. There are relatively few studies on the relationship between psychiatric and substance...
Authors: Lincoln I Khasakhala, David M Ndetei and Muthoni Mathai
Repetitive transcranial magnetic stimulation (rTMS) can enhance the excitement of the brain through adjusting the biological activities of the cerebral cortex and has wide biological effects, making it one bas...
Authors: Eylem Ozten, Gokben Hizli Sayar and Oguz Karamustafalioglu
During the last decade, there was a debate concerning the true efficacy of antidepressants. Several papers were published in scientific journals, but many articles were also published in the lay press and the ...
Authors: Konstantinos N Fountoulakis, Cyril Hoschl, Siegfried Kasper, Juan Lopez-Ibor and Hans-Jürgen Möller
Patients’ informed consent prior to treatment initiation is an essential component of contemporary clinical practice, but sometimes, patients lack decision-making capacity for treatment. Such capacity can be r...
The advent of global clinical trials has necessitated the use of English-based rating instruments in diverse cultures where English is clearly not the primary language. The cross-cultural applicability of rati...
Authors: Steven D Targum, Atsuo Nakagawa and Yuji Sato
It has been estimated that as many as two thirds of patients with
schizophrenia are unable to perform basic personal and social roles or
activities. Occupational functioning and social functioning, as well as
...
Authors: Philip Gorwood, Tom Burns, Georg Juckel, Alessandro Rossi, Luis San, Ludger Hargarter and Andreas Schreiner
This case report details the therapeutic effects of tandospirone on two patients
with anorexia nervosa, one with the restricting subtype (ANR), and another with
the binge-eating/purging subtype (ANBP). A 22-ye...
Authors: Kyoji Okita, Akihiro Shiina, Michiko Nakazato and Masaomi Iyo
One of the most intriguing frontiers of current neuroscientific research is represented by the investigation of the possible neural substrates of morality. The assumption is that in humans an innate moral sens...
Quality of life (QoL) is increasingly recognized as a critical outcome parameter in mental health studies. The aim of this study was to investigate different domains of the QoL in persons with obsessive-compul...
Authors: Elisabeth Hertenstein, Nicola Thiel, Nirmal Herbst, Tobias Freyer, Christoph Nissen, Anne Katrin Külz and Ulrich Voderholzer
The changes in the organization of mental health care services have made the role of the family even more important in caring for patients with mental disorders. Caring may have serious consequences for family...
Authors: Vasiliki Sapouna, Vasilis Dafermos, Marios Chatziarsenis, Victoria Vivilaki, Panos Bitsios, Aart H Schene and Christos Lionis
The clinical global impression of severity (CGI-S) scale is a frequently used rating instrument for the assessment of global severity of illness in Central Nervous System (CNS) trials. Although scoring guideli...
Authors: Steven D Targum, Celine Houser, Joanne Northcutt, Jessica A Little, Andrew J Cutler and David P Walling
While indicated for schizophrenia and acute mania, ziprasidone’s evidence base and use in clinical practice extends beyond these regulatory approvals. We, an invited panel of experts led by a working group of ...
Authors: David M Gardner, Andrea L Murphy, Stan Kutcher, Serge Beaulieu, Carlo Carandang, Alain Labelle, Pierre Lalonde, Ashok Malla, Heather Milliken, Claire O’Donovan, Ayal Schaffer, Jorge Soni, Valerie H Taylor and Richard Williams
The objective of this study was to quantify the direct medical resources used and the corresponding burden of disease in the treatment of patients with schizophrenia. Because low-frequency administration (LFA)...
Authors: Nicolas M Furiak, James C Gahn, Robert W Klein, Stephen B Camper and Kent H Summers
This paper applies the Biobehavioral Family Model (BBFM) of stress- related illness to the study and treatment of an adolescent with intractable asthma. The model is described, along with supportive research f...
Authors: Maria Theodoratou-Bekou, Ourania Andreopoulou, Panoraia Andriopoulou and Beatrice Wood
The topic of sexual obsessions as a psychiatric symptom has not been well investigated. The aim of this study was twofold: 1) to explore the presence of sexual obsessions in patients with mood disorders (n=156), ...
The aim of the study was to examine a possible trauma type related variance in the gender difference of posttraumatic stress disorder (PTSD) prevalence.
Several lines of evidence implicate orbitofrontal cortex dysfunction in the pathophysiology of obsessive-compulsive disorder (OCD). The purpose of this study was to investigate neuropsychological dysfunction o...
Studies of the associations between diet and depression have primarily focused on single nutrients or foods. Recently, dietary patterns representing a combination of foods have attracted more interest than ind...
Authors: Norio Sugawara, Norio Yasui-Furukori, Shoko Tsuchimine, Ayako Kaneda, Koji Tsuruga, Kaori Iwane, Noriyuki Okubo, Ippei Takahashi and Sunao Kaneko
The aim of the study was to determine the most common treatment strategies and their costs for patients with an inadequate response to first-line antidepressant treatment (AD) in primary care.
Authors: Antoni Sicras-Mainar, Jorge Maurino, Luis Cordero, Milagrosa Blanca-Tamayo and Ruth Navarro-Artieda
Studies performed to assess the relevance of duration of untreated psychosis (DUP) as a predictor of long-term outcome (i.e. follow-ups of ten years or more) are somewhat limited. The aim of this study was to ...
Authors: Diego Primavera, Chiara Bandecchi, Tiziana Lepori, Lucia Sanna, Eraldo Nicotra and Bernardo Carpiniello
A limited number of studies have assessed the pathways to care of patients experiencing psychosis for the first time. Helpline/clinic programs may offer patients who are still functional but have potential for...
Authors: Amresh K Shrivastava, Megan E Johnston, Larry Stitt, Meghana Thakar, Gopa Sakel, Sunita Iyer, Nilesh Shah and Yves Bureau
Dopamine dysregulation syndrome (DDS) consists of a series of complications such as compulsive use of dopaminergic medications, aggressive or hypomanic behaviors during excessive use, and withdrawal states cha...
Authors: Jin Mizushima, Keisuke Takahata, Noriko Kawashima and Motoichiro Kato
Patients having chronic schizophrenia with frequent relapses and hospitalizations represent a great challenge, both clinically and financially. Risperidone long-acting injection (RIS-LAI) has been the main LAI...
Authors: Thomas R Einarson, Maria Geitona, Alexandros Chaidemenos, Vasiliki Karpouza, Theodoros Mougiakos, Periklis Paterakis, Dimitrios Ploumpidis, Dionyssios Potamitis-Komis, Roman Zilbershtein, Colin Vicente, Charles Piwko, Panagiotis Kakkavas, Konstantina Paparouni, Rasmus C D Jensen and Michiel E H Hemels
Experience of common health symptoms without a clear physical or psychological cause, such as headache or dizziness, is often reported in adolescence. The present study attempted to investigate associations of...
Authors: Dimitra Petanidou, George Giannakopoulos, Chara Tzavara, Christine Dimitrakaki, Ulricke Ravens-Sieberer, Gerasimos Kolaitis and Yannis Tountas
Several psychiatric conditions, both internalizing and externalizing, have been documented in comorbidity with Asperger Syndrome (AS) and High Functioning Autism (HFA). In this review we examine the interplay ...
Authors: Luigi Mazzone, Liliana Ruta and Laura Reale
The primary objective of this study was to evaluate long-term (24-week) safety of eszopiclone in elderly and nonelderly Japanese patients with chronic insomnia. The secondary objectives were to evaluate short-...
Authors: Naohisa Uchimura, Atsushi Kamijo and Takao Takase
The assessment of functioning and disability is an important part of the clinical evaluation, since it measures disease burden and reflects the effectiveness of therapeutic planning and interventions. The aim ...
Authors: Konstantinos N Fountoulakis, Eirini Lekka, Evangelia Kouidi, Ioanna Chouvarda, Asterios Deligiannis and Nickolaos Maglaveras
About 25% of schizophrenia patients with auditory hallucinations are refractory to pharmacotherapy and electroconvulsive therapy. We conducted a deep transcranial magnetic stimulation (TMS) pilot study in orde...
Authors: Oded Rosenberg, Roman Gersner, Limor Dinur Klein, Moshe Kotler, Abraham Zangen and Pinhas Dannon
This case is of 54-year-old female with catatonic schizophrenia, characterized by treatment resistance to the pharmacotherapy with olanzapine, risperidone, flunitrazepam, and ECT. Olanzapine and risperidone an...
Recently, a relationship between obesity and schizophrenia has been reported. Although fat- mass and fat free mass have been shown to be more predictive of health risk than body mass index, there are limited f...
Patients who self-poison have high repetition and high mortality rates. Therefore, appropriate follow-up is important. The aims of the present work were to study treatment received, satisfaction with health ca...
Authors: Tine K Grimholt, Mari A Bjornaas, Dag Jacobsen, Gudrun Dieserud and Oivind Ekeberg
An imbalance in the production of proinflammatory and anti-inflammatory cytokines may play a role in the pathophysiology of perimenopausal depression. The aim of this study was to examine serum levels of the p...
Authors: Sokratis E Karaoulanis, Alexandros Daponte, Katerina A Rizouli, Andreas A Rizoulis, Georgios A Lialios, Catherine T Theodoridou, Christos Christakopoulos and Nikiforos V Angelopoulos
Despite the achievements of previous research, caregiving assessments in severe mental illness should be crossculturally validated in order to define risk groups or to evaluate family work. This study reports ...
Authors: Manuel Gonçalves-Pereira, Bob van Wijngaarden, Miguel Xavier, Ana L Papoila, José M Caldas-de-Almeida and Aart H Schene
Few studies have analyzed predictors of length of stay (LOS) in patients admitted due to acute bipolar manic episodes. The purpose of the present study was to estimate LOS and to determine the potential sociod...
Authors: Manuel Martin-Carrasco, Ana Gonzalez-Pinto, Jaime L Galan, Javier Ballesteros, Jorge Maurino and Eduard Vieta
Many effective treatments for nicotine addiction inhibit noradrenaline reuptake. Three recent studies have suggested that another noradrenaline reuptake inhibitor, atomoxetine, may reduce smoking behaviors.
There have been a limited number of studies comparing bone mass between patients with schizophrenia and the general population. The aim of this study was to compare the bone mass of schizophrenia patients with...
The objective of this study was to assess sentinel event analysis and relative factors in different mental healthcare settings. In addition, the occurrence of sentinel events in different hospital settings was...
Authors: Yi-Lung Chen, Dong-Sheng Tzeng, Ting-Sheng Cheng and Chien-Hung Lin
The KIDSCREEN-52 is a worldwide instrument for measuring health-related quality of life (HRQoL) in children and adolescents. The aim of this study is to assess reliability and validity of the Greek version of ...
Authors: Chara Tzavara, Anastasia Tzonou, Ioannis Zervas, Ulricke Ravens-Sieberer, Christine Dimitrakaki and Yannis Tountas
We previously reported a case in which steroid-induced psychosis was eliminated with risperidone treatment in a patient with polyarteritis nodosa (PN). In the present report, we longitudinally tracked the seru...
Authors: Reiji Yoshimura, Kosuke Saito, Tadanori Terada, Naoki Yunoue, Wakako Umene-Nakano, Shintaro Hirata, Kazuyoshi Saitoh, Yoshiya Tanaka and Jun Nakamura
A standardized definition of remission criteria in schizophrenia was proposed by the International group of NC Andreasen in 2005 (low symptom threshold for the eight core Positive and Negative Syndrome Scale (...
Authors: Sergey N Mosolov, Andrey V Potapov and Uriy V Ushakov
