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  1. Early childhood education services create potentially optimal opportunities to identify and respond effectively to preschoolers' mental health problems. However, little is known about the knowledge, skills and...

    Authors: George Giannakopoulos, Eirini Agapidaki, Christine Dimitrakaki, Despoina Oikonomidou, Dimitra Petanidou, Lia Tsermidou, Gerasimos Kolaitis, Yannis Tountas and Kalliroi Papadopoulou

    Citation: Annals of General Psychiatry 2014 13:1

    Content type: Primary research

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  2. Patients under antipsychotic treatment for schizophrenia commonly exhibit poor adherence to treatment, high rates of treatment discontinuation, and frequent treatment changes. The ETOS study aimed to identify ...

    Authors: Andreas Roussidis, Christina Kalkavoura, Dimos Dimelis, Afroditi Theodorou, Ina Ioannidou, Eleytherios Mellos, Triantafyllia Mylonaki, Areti Spyropoulou and Andreas Yfantis

    Citation: Annals of General Psychiatry 2013 12:42

    Content type: Primary research

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  3. Patient satisfaction is an important outcome variable that is increasingly used in mental health service evaluation. There are no results available for patients with obsessive-compulsive disorder (OCD) yet.

    Authors: Paraskevi Mavrogiorgou, Frauke Siebers, Georg Juckel and Thorsten Kienast

    Citation: Annals of General Psychiatry 2013 12:41

    Content type: Primary research

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  4. Patients with schizophrenia often experience comorbid obsessive-compulsive symptoms. Within these patients, a significant subgroup developed secondary obsessive-compulsive symptoms during treatment with clozap...

    Authors: Gül Eryılmaz, Gökben Hızlı Sayar, Eylem Ozten, Işıl Gögcegöz Gül and Oğuz Karamustafalıoğlu

    Citation: Annals of General Psychiatry 2013 12:40

    Content type: Case report

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  5. The aim was to identify potential risk factors for lethal outcome in patients with delirium tremens (DT) treated in the psychiatric setting.

    Authors: Dragana Ignjatovic-Ristic, Nemanja Rancic, Slobodan Novokmet, Slobodan Jankovic and Srdjan Stefanovic

    Citation: Annals of General Psychiatry 2013 12:39

    Content type: Primary research

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  6. Type D personality has been associated with a variety of emotional and social difficulties as well as with poor prognosis in patients with established coronary heart disease (CHD). We examined the psychometric...

    Authors: Christos Christodoulou, Athanasios Douzenis, Paula MC Mommersteeg, Loukianos Rallidis, Antonis Poulios, Vasiliki Efstathiou, Georgios Bouras, Christos Varounis, Panagiota Korkoliakou, John Palios, Dimitrios Th Kremastinos and Lefteris Lykouras

    Citation: Annals of General Psychiatry 2013 12:38

    Content type: Primary research

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  7. Maternal depression has a negative impact on both the mother and child's physical and mental health, as well as impairs parenting skills and pediatric health care utilization. The pediatricians' role in identi...

    Authors: Eirini Agapidaki, Kyriakos Souliotis, Stylianos Christogiorgos, lannis Zervas, Angeliki Leonardou, Gerasimos Kolaitis, George Giannakopoulos, Christina Dimitrakaki and Yannis Tountas

    Citation: Annals of General Psychiatry 2013 12:37

    Content type: Primary research

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  8. Whether depression or cardiovascular disease would have a greater effect on worsening cognitive impairment in the burgeoning older elderly population is uncertain. Which disorder causes greater cognitive impai...

    Authors: Yun-Hsuan Chang, Mu-En Liu, Chih-Chun Huang, Yan-Chiou Ku, Sheng-Yu Lee, Shiou-Lan Chen, Wen-Chien Liu and Ru-Band Lu

    Citation: Annals of General Psychiatry 2013 12:36

    Content type: Primary research

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  9. In South Korea, it has not been easy to negotiate studies that target drug users who are being punished by law, and accordingly, no study on suicidal ideation among substance users has been accomplished yet. I...

    Authors: Min Kwon, Soo Yang, Kyongran Park and Dai-Jin Kim

    Citation: Annals of General Psychiatry 2013 12:35

    Content type: Primary research

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  10. Adolescence represents one of the critical transitions in the life span and is characterized by a tremendous pace in growth and change that is second only to that of infancy. Both biological and psychological ...

    Authors: Concetta De Pasquale, Maria Luisa Pistorio, Eleonora Tornatore, Domenico De Berardis and Michele Fornaro

    Citation: Annals of General Psychiatry 2013 12:34

    Content type: Primary research

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  11. Several studies have reported significantly higher stress levels, both short and long terms, among mothers giving preterm birth compared with mothers giving birth at term. Stress, however, is a psychological p...

    Authors: Aud R Misund, Per Nerdrum, Stein Bråten, Are Hugo Pripp and Trond H Diseth

    Citation: Annals of General Psychiatry 2013 12:33

    Content type: Primary research

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  12. Relapse in patients with schizophrenia has devastating repercussions, including worsening symptoms, impaired functioning, cognitive deterioration and reduced quality of life. This progressive decline exacerbat...

    Authors: José M Olivares, Jan Sermon, Michiel Hemels and Andreas Schreiner

    Citation: Annals of General Psychiatry 2013 12:32

    Content type: Review

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  13. Several lines of evidence suggest that dysfunction of the dorsolateral prefrontal cortex (DLPFC) and orbitofrontal cortex (OFC) contributes to the pathophysiology of pervasive developmental disorders (PDD). Th...

    Authors: Tetsuji Sawa, Masaki Kodaira, Arata Oiji, Daimei Sasayama, Yoshitaka Iwadare, Hirokage Ushijima, Masahide Usami, Kyota Watanabe and Kazuhiko Saito

    Citation: Annals of General Psychiatry 2013 12:31

    Content type: Primary research

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  14. Individuals with posttraumatic stress disorder (PTSD) are more likely to undertake harmful health behaviors like substance use. Less is known about the association of PTSD with healthful behaviors such as heal...

    Authors: Kathryn M Godfrey, Laurie A Lindamer, Sheeva Mostoufi and Niloofar Afari

    Citation: Annals of General Psychiatry 2013 12:30

    Content type: Primary research

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  15. The 22q11.2 deletion syndrome is caused by a microdeletion of chromosome 22. One third of all patients with 22q11.2 deletion develop schizophrenia-like symptoms. In general, the prevalence of 22q11.2 deletion ...

    Authors: Kazutaka Ohi, Ryota Hashimoto, Hidenaga Yamamori, Yuka Yasuda, Michiko Fujimoto, Noriko Nakatani, Kouzin Kamino and Masatoshi Takeda

    Citation: Annals of General Psychiatry 2013 12:29

    Content type: Case report

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  16. The Subjective Well-Being Under Neuroleptic Treatment Scale short form (SWN-K) is a self-rating scale developed to measure mentally ill patients' well-being under the antipsychotic drug treatment. This paper r...

    Authors: Liina Haring, René Mõttus, Peeter Jaanson, Raine Pilli, Kairi Mägi and Eduard Maron

    Citation: Annals of General Psychiatry 2013 12:28

    Content type: Primary research

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  17. Caring for individuals with schizophrenia can create distress for caregivers which can, in turn, have a harmful impact on patient progress. There could be a better understanding of the connections between care...

    Authors: Shyhrete Rexhaj, Nataly Viens Python, Diane Morin, Charles Bonsack and Jérôme Favrod

    Citation: Annals of General Psychiatry 2013 12:27

    Content type: Primary research

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  18. During the last decade, a number of meta-analyses questioned the clinically relevant efficacy of antidepressants. Part of the debate concerned the method used in each of these meta-analyses as well as the qual...

    Authors: Konstantinos N Fountoulakis, Areti Angeliki Veroniki, Melina Siamouli and Hans-Jürgen Möller

    Citation: Annals of General Psychiatry 2013 12:26

    Content type: Review

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  19. Cushing’s syndrome can present with a spectrum of symptoms; however, it is less recognised that psychiatric symptoms can form part of the clinical presenting features. In the investigations for an organic caus...

    Authors: Alice Tang, Anthony J O’Sullivan, Terry Diamond, Andrew Gerard and Peter Campbell

    Citation: Annals of General Psychiatry 2013 12:23

    Content type: Case report

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  20. Increasing availability and use of long-acting injectable antipsychotics have generated a need to compare these formulations with their oral equivalents; however, a paucity of relevant data is available.

    Authors: Michael Markowitz, Dong-Jing Fu, Bennett Levitan, Srihari Gopal, Ibrahim Turkoz and Larry Alphs

    Citation: Annals of General Psychiatry 2013 12:22

    Content type: Primary research

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  21. Annual suicide rates of Hungary were unexpectedly high in the previous century. In our narrative review, we try to depict, with presentation of the raw data, the main descriptive epidemiological features of th...

    Authors: Zoltan Rihmer, Xenia Gonda, Balazs Kapitany and Peter Dome

    Citation: Annals of General Psychiatry 2013 12:21

    Content type: Review

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  22. It has been reported that oral health is poor in elderly populations and is associated with poor cognition and dementia. The objective of this study was to examine the association between tooth loss and cognit...

    Authors: Yuki Saito, Norio Sugawara, Norio Yasui-Furukori, Ippei Takahashi, Shigeyuki Nakaji and Hiroto Kimura

    Citation: Annals of General Psychiatry 2013 12:20

    Content type: Primary research

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  23. This observational study documented heart rate over the entire course of electrically induced seizures and aimed to evaluate the effects of stimulus electrode placement, patients' age, stimulus dose, and addit...

    Authors: Josef Nagler

    Citation: Annals of General Psychiatry 2013 12:19

    Content type: Primary research

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  24. Little focus has been paid to the role of poor mental health and childhood abuse among young people with regard to human immunodeficiency virus (HIV) risk behaviour and HIV prevention in Africa. The aim of thi...

    Authors: Karl Peltzer, Supa Pengpid and Issaka Tiembre

    Citation: Annals of General Psychiatry 2013 12:18

    Content type: Primary research

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  25. Considered as a moment of psychological vulnerability, adolescence is remarkably a risky period for the development of psychopathologies, when the choice of the correct therapeutic approach is crucial for achi...

    Authors: Nádia NR Lima, Vânia B Nascimento, Jorge AC Peixoto, Marcial M Moreira, Modesto LR Neto, José C Almeida, Carlos AC Vasconcelos, Saulo A Teixeira, Jucier G Júnior, Francisco TC Junior, Diego DM Guimarães, Aline Q Brasil, Jesus S Cartaxo, Marco Akerman and Alberto OA Reis

    Citation: Annals of General Psychiatry 2013 12:17

    Content type: Review

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  26. Khat is a well-known natural stimulant from the Catha edulis plant and is widely used in certain Red Sea countries, including Yemen and the province of Jazan in Saudi Arabia. Jazan is located in the southwestern ...

    Authors: Mohamed Salih Mahfouz, Rashad Mohammed Alsanosy and Abdelrahim Mutwakel Gaffar

    Citation: Annals of General Psychiatry 2013 12:16

    Content type: Primary research

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  27. Studies on mental health problems during childhood and youth development phases have reported that families of children diagnosed with a depressive disorder tend to be dysfunctional. These dysfunctions have be...

    Authors: Lincoln I Khasakhala, David Musyimi Ndetei, Muthoni Mathai and Valerie Harder

    Citation: Annals of General Psychiatry 2013 12:15

    Content type: Primary research

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  28. The therapeutic alliance is related to better course and outcome of treatment in schizophrenia. This study explores predictors and characteristics of the therapeutic alliance in recent-onset schizophrenia spec...

    Authors: Ragnhild Johansen, Valentina C Iversen, Ingrid Melle and Knut A Hestad

    Citation: Annals of General Psychiatry 2013 12:14

    Content type: Primary research

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  29. Suicide is a major cause of death among youths particularly with psychiatric, alcohol abuse and substance abuse disorders. There are relatively few studies on the relationship between psychiatric and substance...

    Authors: Lincoln I Khasakhala, David M Ndetei and Muthoni Mathai

    Citation: Annals of General Psychiatry 2013 12:13

    Content type: Primary research

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  30. Repetitive transcranial magnetic stimulation (rTMS) can enhance the excitement of the brain through adjusting the biological activities of the cerebral cortex and has wide biological effects, making it one bas...

    Authors: Eylem Ozten, Gokben Hizli Sayar and Oguz Karamustafalioglu

    Citation: Annals of General Psychiatry 2013 12:12

    Content type: Case report

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  31. During the last decade, there was a debate concerning the true efficacy of antidepressants. Several papers were published in scientific journals, but many articles were also published in the lay press and the ...

    Authors: Konstantinos N Fountoulakis, Cyril Hoschl, Siegfried Kasper, Juan Lopez-Ibor and Hans-Jürgen Möller

    Citation: Annals of General Psychiatry 2013 12:11

    Content type: Commentary

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  32. Patients’ informed consent prior to treatment initiation is an essential component of contemporary clinical practice, but sometimes, patients lack decision-making capacity for treatment. Such capacity can be r...

    Authors: Nikolaos Bilanakis, Aikaterini Vratsista, Georgios Kalampokis, Georgios Papamichael and Vaios Peritogiannis

    Citation: Annals of General Psychiatry 2013 12:10

    Content type: Primary research

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  33. It has been estimated that as many as two thirds of patients with schizophrenia are unable to perform basic personal and social roles or activities. Occupational functioning and social functioning, as well as ...

    Authors: Philip Gorwood, Tom Burns, Georg Juckel, Alessandro Rossi, Luis San, Ludger Hargarter and Andreas Schreiner

    Citation: Annals of General Psychiatry 2013 12:8

    Content type: Primary research

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  34. This case report details the therapeutic effects of tandospirone on two patients with anorexia nervosa, one with the restricting subtype (ANR), and another with the binge-eating/purging subtype (ANBP). A 22-ye...

    Authors: Kyoji Okita, Akihiro Shiina, Michiko Nakazato and Masaomi Iyo

    Citation: Annals of General Psychiatry 2013 12:7

    Content type: Case report

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  35. One of the most intriguing frontiers of current neuroscientific research is represented by the investigation of the possible neural substrates of morality. The assumption is that in humans an innate moral sens...

    Authors: Donatella Marazziti, Stefano Baroni, Paola Landi, Diana Ceresoli and Liliana Dell’Osso

    Citation: Annals of General Psychiatry 2013 12:6

    Content type: Review

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  36. Quality of life (QoL) is increasingly recognized as a critical outcome parameter in mental health studies. The aim of this study was to investigate different domains of the QoL in persons with obsessive-compul...

    Authors: Elisabeth Hertenstein, Nicola Thiel, Nirmal Herbst, Tobias Freyer, Christoph Nissen, Anne Katrin Külz and Ulrich Voderholzer

    Citation: Annals of General Psychiatry 2013 12:4

    Content type: Primary research

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  37. The changes in the organization of mental health care services have made the role of the family even more important in caring for patients with mental disorders. Caring may have serious consequences for family...

    Authors: Vasiliki Sapouna, Vasilis Dafermos, Marios Chatziarsenis, Victoria Vivilaki, Panos Bitsios, Aart H Schene and Christos Lionis

    Citation: Annals of General Psychiatry 2013 12:3

    Content type: Primary research

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  38. The clinical global impression of severity (CGI-S) scale is a frequently used rating instrument for the assessment of global severity of illness in Central Nervous System (CNS) trials. Although scoring guideli...

    Authors: Steven D Targum, Celine Houser, Joanne Northcutt, Jessica A Little, Andrew J Cutler and David P Walling

    Citation: Annals of General Psychiatry 2013 12:2

    Content type: Primary research

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  39. While indicated for schizophrenia and acute mania, ziprasidone’s evidence base and use in clinical practice extends beyond these regulatory approvals. We, an invited panel of experts led by a working group of ...

    Authors: David M Gardner, Andrea L Murphy, Stan Kutcher, Serge Beaulieu, Carlo Carandang, Alain Labelle, Pierre Lalonde, Ashok Malla, Heather Milliken, Claire O’Donovan, Ayal Schaffer, Jorge Soni, Valerie H Taylor and Richard Williams

    Citation: Annals of General Psychiatry 2013 12:1

    Content type: Review

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  40. The objective of this study was to quantify the direct medical resources used and the corresponding burden of disease in the treatment of patients with schizophrenia. Because low-frequency administration (LFA)...

    Authors: Nicolas M Furiak, James C Gahn, Robert W Klein, Stephen B Camper and Kent H Summers

    Citation: Annals of General Psychiatry 2012 11:29

    Content type: Primary research

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  41. This paper applies the Biobehavioral Family Model (BBFM) of stress- related illness to the study and treatment of an adolescent with intractable asthma. The model is described, along with supportive research f...

    Authors: Maria Theodoratou-Bekou, Ourania Andreopoulou, Panoraia Andriopoulou and Beatrice Wood

    Citation: Annals of General Psychiatry 2012 11:28

    Content type: Case report

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  42. The topic of sexual obsessions as a psychiatric symptom has not been well investigated. The aim of this study was twofold: 1) to explore the presence of sexual obsessions in patients with mood disorders (n=156), ...

    Authors: Liliana Dell’Osso, Giulia Casu, Marina Carlini, Ciro Conversano, Paola Gremigni and Claudia Carmassi

    Citation: Annals of General Psychiatry 2012 11:27

    Content type: Primary research

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  43. Several lines of evidence implicate orbitofrontal cortex dysfunction in the pathophysiology of obsessive-compulsive disorder (OCD). The purpose of this study was to investigate neuropsychological dysfunction o...

    Authors: Masaki Kodaira, Yoshitaka Iwadare, Hirokage Ushijima, Arata Oiji, Motoichiro Kato, Nobuhiro Sugiyama, Daimei Sasayama, Masahide Usami, Kyota Watanabe and Kazuhiko Saito

    Citation: Annals of General Psychiatry 2012 11:25

    Content type: Primary research

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  44. Studies of the associations between diet and depression have primarily focused on single nutrients or foods. Recently, dietary patterns representing a combination of foods have attracted more interest than ind...

    Authors: Norio Sugawara, Norio Yasui-Furukori, Shoko Tsuchimine, Ayako Kaneda, Koji Tsuruga, Kaori Iwane, Noriyuki Okubo, Ippei Takahashi and Sunao Kaneko

    Citation: Annals of General Psychiatry 2012 11:24

    Content type: Primary research

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  45. Studies on the ‘self-medication hypothesis’ have focused on substance abuse as an attempt to alleviate emotional suffering.

    Authors: Icro Maremmani, Angelo Giovanni Icro Maremmani, Fabio Rugani, Luca Rovai, Matteo Pacini, Silvia Bacciardi, Joseph Deltito, Liliana Dell’Osso and Hagop S Akiskal

    Citation: Annals of General Psychiatry 2012 11:23

    Content type: Primary research

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